USA experimental COVID-19 vaccine protects airways in nonhuman primates

Moderna's Covid vax shows great result in monkeys

Russia claims success in producing COVID-19 vaccine

"Our best hope of controlling COVID-19 is with a vaccine", Dr. Marcus Zervos, chief of infectious disease for Henry Ford, says in a statement. "Russian Federation will have got there first", he added.

Moderna is working closely with the USA government.

Clinical trials on another 1,600 people will start after the registration and will continue along with the production.

A spokesperson for Moderna declined to comment on the company's pricing plans, citing in an email to Fierce Pharma the confidentiality of "discussions with a number of governments and governmental entities about potential supply of mRNA-1273". Pfizer and BioNTech's first vaccine targeted a piece of the spike protein, a structure the virus uses to infect human cells. The Gamaleya Institute in Russian Federation, which carried out trials of its own experimental vaccine, is relying on scientific knowledge acquired six years ago in the fight against Ebola and the Middle East respiratory syndrome (Mers), a viral respiratory disease caused by a novel coronavirus, Mr Dmitriev said.

The vaccine, which has been created by the Moscow-based Gamaleya Institute, will be available for frontline healthcare workers first.

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Russians have also contacted Sao Paulo's Butantan Institute to discuss testing their vaccine, the institute's director told reporters on Wednesday. "What it does is it produces an immune response or an antibody response".

AstraZeneca PLC, Moderna Inc. and Pfizer Inc. have begun late-stage testing for Covid-19 vaccines, with initial results from some of the human trials expected as soon as October. Half the participants will receive 2 shots of their vaccine 28 days apart, while the other half will receive 2 shots of the saltwater placebo.

A rival vaccine being developed by AstraZeneca and Oxford University - among the most advanced in human trials - in a similar animal study also appeared to prevent damage to the lungs and keep the virus from making copies of itself there.

The conference also saw speakers from several leading research institutions in Europe as well representatives from collectives such as the Coalition for Epidemic Preparedness that are involved in myriad vaccine development projects.

The researchers from National Institute of Allergy and Infectious Diseases in the United States and the Oxford University found that the ChAdOx1 nCoV-19 vaccine protects the macaques from COVID-19 pneumonia - a complication of SARS-CoV-2 infection in which the lungs become inflamed and may fill with fluid. The primates were Indian-origin rhesus macaques (age 3-6 years) and there were 12 male and 12 female who were stratified into one of the three study arms. The allegations have been denied by Moscow.

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