For now, there is no doubt that thousands of people in the United Kingdom have already been exposed to Covid-19 and will have built up immunity, and that that will continue as people continue to move around freely.
Speaking at a press conference following the emergency Cobra meeting, the PM said the disease "continues and will continue to spread" and called it the "worst public health crisis in a generation".
Only people in hospital would be tested, he said, adding that schools will be asked to cancel foreign trips and elderly people or those in poor health were told not to go on cruise ships.
Those with a high temperature or cough should stay at home for seven days, he said.
And Public Health England confirmed that 460 people had been diagnosed across Britain following the largest increase in a single day.
He said the evidence suggests it will "have little effect on the spread" of coronavirus, though such events did place a burden on public services.
Chelsea's full squad has also gone into self-isolation after winger Callum Hudson-Odoi tested positive for coronavirus.
Mr Trudeau's office said he is feeling well and will continue to work.
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Ireland will shut schools, universities and childcare facilities until March 29 and restrict mass gatherings to slow the spread of the coronavirus, acting Prime Minister Leo Varadkar said on Thursday. I know how worrying this time is for so many.
He added: 'At all stages, we have been guided by the science, and we will do the right thing at the right time'.
'We want to supress it, not get rid of it completely - which you can't do anyway - not supress it so we get the second peak, and also allow enough of us who are going to get mild illness, to become immune to this to help with the whole population response, which would help everybody'.
- The FTSE 100 closed down by more than 10% on Thursday as fears over Covid-19 sparked the index's worst bloodbath since 1987, while markets fell in Asia on Friday.
If you take their projection that there is a fair chance that if you just let this spread through the population, albeit hopefully in a controlled way, 70 percent of the British population will get infected, even in a better case scenario in which 0.5 percent or one percent die, you're still looking at three to 500,000 deaths with that approach.
She said was "disappointed" with the lack of detail and "minimal changes" in the policy laid out by the Prime Minister, Chief Medical Officer and Chief Scientific Adviser in the news conference.
- The Players Championship golf tournament in Florida was cancelled after one round with organisers saying it was "the right thing to do" because of the virus spread.
Johnson said those showing symptoms of having the virus should self-isolate for at least a week.